Level of serum undercarboxylated osteocalcin correlates with bone quality assessed by calcaneal quantitative ultrasound sonometry in young Japanese females

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Determinants and correlates of serum undercarboxylated osteocalcin.

BACKGROUND/AIMS To assess dietary and nondietary determinants of serum undercarboxylated osteocalcin (ucOC) as a measure of vitamin K status. METHODS UcOC and total intact osteocalcin (iOC) concentrations were determined by specific ELISA tests in serum samples of 231 male and 320 female participants (18-81 years) of the representative, cross-sectional Bavarian Food Consumption Survey II. Det...

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Dietary antioxidant quality score (DAQs) is associated with bone mass assessed by calcaneal quantitative ultrasound in young women

INTRODUCTION Evidence suggests that intake of antioxidants could positively influence bone mass by preventing bone metabolism against oxidative stress. OBJECTIVE We aimed to investigate the possible influence of single antioxidant intakes and dietary antioxidant quality score (DAQs) on calcaneal quantitative ultrasound (QUS) in a population of young adults. METHODS A total of 605 young Span...

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Analysis of serum undercarboxylated osteocalcin level in rats with type 2 diabetes mellitus and the correlation with cognitive impairment

The aim of the study was to investigate the correlation between the serum undercarboxylated osteocalcin (ucOC) level and the blood biochemistry and cognitive impairment in rats with type 2 diabetes mellitus (T2DM). Sprague-Dawley (SD) rats were randomly divided into the normal control group (NC) and type 2 DM group. DM group received the high-fat and high-sugar diet combined with the intraperit...

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Eldecalcitol Reduces Serum Undercarboxylated Osteocalcin Levels Along with a Decreased Bone Metabolic Turnover in Patients with Osteoporosis

Undercarboxylated osteocalcin (ucOC) is a marker of vitamin K deficiency. In addition, ucOC reflects bone metabolic turnover besides vitamin K sufficiency status. Increased ucOC level is considered a predictor of proximal femoral fracture. Eldecalcitol has been reported to strongly influence bone metabolism as compared with the conventional vitamin D supplementation. In this study, we examined ...

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Quantitative ultrasound measurements of stiffness index in young adult females

Background: The aim of the study was to investigate the use of quantitative ultrasound (QUS) in the young (20-25years) Saudi females to obtain stiffness index values related to bone quality. Method & Findings: In 101 young females recruited, QUS measurements were performed in the calcaneus region. 33% and 3% had osteopenia and osteoporosis in the calcaneus respectively, stiffness index values =...

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ژورنال

عنوان ژورنال: Experimental and Therapeutic Medicine

سال: 2017

ISSN: 1792-0981,1792-1015

DOI: 10.3892/etm.2017.4206